[Funded Projects] - Title

IIT Projects Search

2022-2025
Gustincich S., Armirotti A., Athanassiou A., Barberis A., Cancedda L., Cavalli A., De Pietri Tonelli D., De Vivo M., Diaspro A., Girotto S., Grimaldi B., Netti P., Nicassio F., Petrini E., Pompa P.P., Ruocco G., Siciliano V., Tartaglia G.G., Tirelli N., Tonini R., Tucci V., Vicidomini G.
National Center for Gene Therapy and Drugs based on RNA Technology
National Center for Gene Therapy and Drugs based on RNA Technology
National
2022-2024
Cancedda L., Tucci V.
BuPra
Treatment of social, cognitive, and sleep impairment in a mouse model of Prader- Willi syndrome by repurposing of the FDA-approved diuretic Bumetanide.
Foundation
2021-2023
Fumagalli A.
PSYNegrT
Deciphering the Negr1 interacting network in physiological conditions and in psychiatric and neurodevelopmental disorders.
European Ended
2021-2023
Savardi A.
Lejeune 2021 Savardi
Early NKCC1 Inhibition to treat epilepsy and hyperactivity in Down syndrome
Foundation
2019-2021
Portioli C.
3D NKCC1
Interdisciplinary approach to characterize the structure and the ion transport mechanism of NKCC1, a key target for brain disorders.
European Ended
2017-2023
Cancedda L.
GenEdiDS
GenEdiDS: Rescuing Cognitive Deficits in Neurodevelopmental Disorders by Gene Editing in Brain Development: the case of Down Syndrome
European Ended
2016-2018
Cingolani L., Contestabile A.
SAN PAOLO 2015 CINGOLANI
Genome-editing approaches for personalized medicine in inherited diseases
Foundation Ended
2016-2021
Cancedda L.
DTI Cancedda
Targeting aberrant Cl‐ homeostasis and GABAergic transmission in Down syndrome to design innovative therapeutic approaches
In Kind Ended
2014-2017
Cancedda L.
CARIPLO 2013 CANCEDDA
Caratterizzazione fenotipica delle mutazioni di PCDH19 che causano la sindrome 'Epilessia e Ritardo Mentale Femminile (EFMR)' usando modelli in vitro ed in vivo
Foundation Ended
2014-2016
Cancedda L.
LEJEUNE 2014 CANCEDDA
Experimental and clinical evaluation of a clinically-used CI transporter inhibitor to rescue cognitive functions by reverting excitatory GABA in Down syndrome - Part of the study concerning Ts65Dn mice
Foundation Ended
2014-2015
Ghezzi D.
GOAP Ghezzi 2014
Gene editing to treat genetic photoreceptor degeneration
International Ended
2013-2017
Cancedda L.
Telethon 2013 Cancedda
Unravelling the Rett syndrome: effects of MeCP2 mutations on synaptic function
Foundation Ended
2012-2015
Contestabile A.
Lejeune 2012 Contestabile
Safe modulation of GABAergic signaling by a clinically-used inhibitor of chloride transporters to rescue cognitive functions in a mouse model of Down syndrome
Foundation Ended
2010-2014
Cancedda L.
TELETHON 2010 CANCEDDA
Role of GABAA-receptor mutations in idiopathic generalized epilepsy: a developmental study
Foundation Ended
2009-2013
Cancedda L.
SAN PAOLO 2009 CANCEDDA
Early interference with GABA action by exposure to therapeutic drugs: circuit development, epilepsy and cognition
Foundation Ended