Publications
2024
Ruiz Munevar M.J., Rizzi V., Portioli C., Vidossich P., Cao E., Parrinello M., Cancedda L., De Vivo M.
Cation Chloride Cotransporter NKCC1 Operates through a Rocking-Bundle Mechanism
Journal of the American Chemical Society, vol. 146, (no. 1), pp. 552-566
2024
Potenzieri A., Uccella S., Preiti D., Pisoni M., Rosati S., Lavarello C., Bartolucci M., Debellis D., Catalano F., Petretto A., Nobili L., Fellin T., Tucci V., Ramenghi L.A., Savardi A., Cancedda L.
Early IGF-1 receptor inhibition in mice mimics preterm human brain disorders and reveals a therapeutic target
Science advances, vol. 10, (no. 9)
2024
Colombi I., Rastogi M., Parrini M., Alberti M., Potenzieri A., Chellali M.M., Rosati S., Chiappalone M., Nanni M., Contestabile A., Cancedda L.
Heterogeneous subpopulations of GABAAR-responding neurons coexist across neuronal network scales and developmental stages in health and disease
iScience, vol. 27, (no. 4)
2024
Rastogi M., Bartolucci M., Nanni M., Aloisio M., Vozzi D., Petretto A., Contestabile A., Cancedda L.
Integrative multi-omic analysis reveals conserved cell-projection deficits in human Down syndrome brains
Neuron
Article
Journal
2024
Marinaro G., Bruno L., Pirillo N., Coluccio M.L., Nanni M., Malara N., Battista E., Bruno G., De Angelis F., Cancedda L., Di Mascolo D., Gentile F.
The role of elasticity on adhesion and clustering of neurons on soft surfaces
Communications Biology, vol. 7, (no. 1)
2023
Smith J.B., Cancedda L., Jozwiak S., Mercer A.C.
Editorial: Viral vector-based gene therapy in neurological disease: The future is now
Frontiers in Neurology, vol. 14
2023
Prakasam R., Bonadiman A., Andreotti R., Zuccaro E., Dalfovo D., Marchioretti C., Tripathy D., Petris G., Anderson E.N., Migazzi A., Tosatto L., Cereseto A., Battaglioli E., Soraru G., Lim W.F., Rinaldi C., Sambataro F., Pourshafie N., Grunseich C., Romanel A., Pandey U.B., Contestabile A., Ronzitti G., Basso M., Pennuto M.
LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice
Nature Communications, vol. 14, (no. 1)
2023
Savardi A., Patricelli Malizia A., De Vivo M., Cancedda L., Borgogno M.
Preclinical Development of the Na-K-2Cl Co-transporter-1 (NKCC1) Inhibitor ARN23746 for the Treatment of Neurodevelopmental Disorders
ACS Pharmacology and Translational Science, vol. 6, (no. 1), pp. 1-11
2023
Savardi A., Colombi I., Alberti M., Parrini M., Ziogas I., Borgogno M., De Vivo M., Contestabile A., Cancedda L.
Role of Intracellular Chloride Accumulation in Down Syndrome Physiopathology and Therapeutic Strategies
XXI Telethon Scientific Convention
Poster
Conference
2023
Savardi A., Borgogno M., De Vivo M., Cancedda L.
Selective NKCC1 Inhibitors for the Treatment of Drug-Resistant Epilepsy
Discussione in Epilessia Sperimentale 2
Poster
Conference
2023
Savardi A., Borgogno M., De Vivo M., Cancedda L.
Selective NKCC1 Inhibitors for the Treatment of Neurodevelopmental and Neurological Disorders with defective NKCC1/KCC2 expression-ratio
American Academy of Neurology Annual Meeting
Poster
Conference
2022
Cwetsch A.W., Ziogas I., Narducci R., Savardi A., Bolla M., Pinto B., Perlini L.E., Bassani S., Passafaro M., Cancedda L.
A rat model of a focal mosaic expression of PCDH19 replicates human brain developmental abnormalities and behaviours
Brain Communications, vol. 4, (no. 3)
2022
Stuefer A., Balasco L., Bertozzi S., Coletta L., Hayward A., Rocchi F., Montani C., Alvino F., Galbusera A., Aldrighetti M., Gini S., Curcic V., Papaleo F., Iurilli G., Cancedda L., Armirotti A., Bozzi Y., Gozzi A.
Chemogenetic excitation of pyramidal neurons during early development: a longitudinal behavioral and imaging study
SfN
Poster
Conference
2022
Montani C., Hayward A., Gutierrez-Barragan D., Morelli G., Alvino F. G., Coletta L., Galbusera A., Pasqualetti M., Cancedda L., Gozzi A.
Chemogenetic stimulation of oxytocinergic neurons dynamically modulates fMRI connectivity
Annual Meeting of the Society for Neuroscience 2022
Poster
Conference
2022
Montani C., Hayward A., Gutierrez-Barragan D., Morelli G., Alvino F., Coletta L., Galbusera A., Rocchi F., Pasqualetti M., Cancedda L., Gozzi A.
Chemogenetic stimulation of oxytocinergic neurons dynamically modulates fMRI connectivity
FENS Forum 2022
Poster
Conference